100 College Street was the first of two towers slated for the developable land created by the Downtown Crossing Project. Currently, 100 College St (500,000 sq. ft.) is fully occupied by researchers from Alexion and Yale University.
Winstanley Enterprises has begun construction on the second bioscience tower at 101 College St. This is in response to the growing demand and to further connect the medical district and downtown area.
There are also other notable construction projects in the works, including 275 South Orange Street (planned construction in 2023, opening in 2025, and spanning 250,000 sq. ft.), Parcel B at Downtown Crossing (with an available site of 200-500,000 sq. ft.), and Science Park (with an available site of 200,000 sq. ft.).